Lead Scientist

Main Responsibilities

 

Development and characterization of innovative formulations (lyophilized, pulverized product) of targeted and/or untargeted microbubbles and nano-emulsions.

 

Development and full characterization of nanodroplets from nano-emulsions.

 

Develop and perform stability studies of experimental batches.

 
Specific Responsibilities

 

1. Conduct Research and Development processes and controls established by company Quality Management System

2. Research and develop formulations

3. Develop in vitro assays for the characterization of the formulations

4. Propose, design, execute and analyze experiments individually and as a team with collaborators, colleagues, and supervisor

5. Perform laboratory work including chemical characterization of chemical intermediates and products formulation

6. Maintain detailed and organized laboratory notebook with detailed observations

7. Peer review laboratory notebooks

8. Analyze, document, and interpret data

9. Prepare and deliver scientific writings and presentations

10. Assist with the preparation of grant proposals, applications, and closeout reports

11. Participate in patent preparation

 
Requirements

 

1. PhD in Pharmaceutical sciences and pharmaceutics combined with a minimum 1-3 years industrial research experience in medical devices and/or pharmaceuticals

2. Knowledge in detection and treatment of cancer, cardiovascular and neurological disorders and experience and skills in organic, biological and analytical chemistry

3. Excellent working knowledge and direct experience in a breadth of analytical tools, materials testing, prototyping/equipment

4. Validated practical experience in design, experimentation, statistics, and data analysis

5. Excellent problem solving capability

6. Excellent written and verbal communication skills

7. Perform the following routine laboratory duties:

- Ensure laboratory areas are clean and organized

- Troubleshoot and perform routine repairs and maintenance of laboratory equipment as needed

- Monitor the status of laboratory supplies

- Maintain weekly schedules and report any changes to the CSO/COO

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Manufacturing/Formulation Scientist

 

Main Responsibilities

 

Develop injectable products based on lipid-based perfluorocarbon micro/nanoemulsions for clinical and commercial use, including product process development and scale-up, product characterization, technology transfer, and GMP manufacturing, 

 

Adhere to cGMP or current good manufacturing practices, standard operating methods and legal regulations to maintain a safe and clean work environment.

 

Document all production efforts in appropriate logs, forms, reports and databases.

 

Specific Responsibilities

1. Lead, design and execute in-process development studies for product manufacturing

2. Develop strategy and product process development and scale up studies for manufacturing of lipid-based perfluorocarbon formulations.

3. Support characterization and manufacturing

4. Develop experimental and supervise plans and execute studies to assess physicochemical stability

5. Work independently with counterparts from other functional areas to deliver on CMC milestones while adhering to broad project timelines

6. Generate, document and compile data for team and senior management discussions,

7. Resolve manufacturing issues, while being mindful of supply chain, quality, and regulatory consideration

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Requirements 

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1. PhD in Biochemistry, Pharmaceutical Sciences, or Engineering combined with a minimum 1-5 years industrial research experience in medical devices and/or pharmaceuticals  OR MS with 5-10 years experience

2. Excellent working knowledge and direct experience in a breadth of analytical tools, materials testing, prototyping/equipment, in vitro assays and in vivo models

3. Validated practical experience in design, experimentation, statistics, and data analysis

4. Excellent problem solving capability

5. Excellent written and verbal communication skills

6. Working knowledge of quality systems and regulatory compliance pertaining to FDA/EU approval

 

Physical Demands

 

 . Ability to bend or stand as necessary. Ability to carry, lift and/or displace larger items/boxes.

 

This job description does not include or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

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CONTACTS:  Emmanuelle Meuillet at e.meuillet@mvtpharma.com to send your CV or if you have any questions. regarding the positions. 

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